Telmisartan (Micardis�/Pritor�) protects against progression of diabetic nephropathy Part 2

Notes to Editor a) The DETAIL survey be an self-directed, investigator-led study support by means of a compromise from Boehringer Ingelheim.

b) Telmisartan (Micardis®/ Pritor®) be discovered and industrialized by Boehringer Ingelheim, Germany. Boehringer Ingelheim market telmisartan underneath the trademark Micardis® bordered by 84 countryside in a circle the world, plus the USA, Japan and chief European countries. In Canada and Australia GlaxoSmithKline (GSK) and Boehringer Ingelheim co-promote telmisartan under the Micardis® trademark. GSK at present promote telmisartan in situation of Pritor® under a co-marketing agreement near Boehringer Ingelheim in 30 countries excluding the USA.

Telmisartan was licensed to GSK from Boehringer Ingelheim in March 1998. The European, centralised marketing authorisation all for telmisartan 40 mg & 80 mg tablets was granted to Boehringer Ingelheim against 11th December 1998.

Furthermore, Boehringer Ingelheim markets telmisartan in dispense and transport with Bayer AG in quite a few European countries, Yamanouchi in Japan and Abbott Laboratories in the USA.

c) Although GFR decline intrinsically with age, in individuals with diabetes, GFR declines at a faster rate indicating the evolution of kidney virus. The target of prescribe an ARB or an ACE inhibitor is to dampen the progression of kidney disease, demonstrated by a let-up in the promptness at which GFR declines.

5) Chia SE. (2000) Endocrine disruptors and mannish reproductive function--a concise appraisal. International Journal of Andrology, 23 Suppl 2:45-6.

3 Esposti LD, et al. Pharmacoeconomics of antihypertensive remedy usage: an analysis of how extensive patients loiter on an mixture of antihypertensive analysis. J Clin Hypertens 2004;6:76-84.

4 Hannedouche T, et al. Evaluation of the refuge and efficacy of telmisartan and enalapril, with the eventual optional extra of frusemide, in moderate-renal ruination patients with mild-to-moderate hypertension. J Renin Angiotensin Aldosterone Syst 2001;2:246-254.

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